Our findings research can provide new insights into the effectiveness of the CO2-assisted co-pyrolysis associated with reduced costs and hazardous wastes.Ambient particulate matter (PM2.5)-induced metabolic syndromes is a critical contributor to the pathological processes of neurological diseases, but the underlying molecular mechanisms remain poorly understood. The rhomboid 5 homolog 2 (Rhbdf2), an essential regulator in the production of TNF-α, has recently been confirmed to exhibit a key role in regulating in?ammation-associated diseases. Thus, we examined whether Rhbdf2 contributes to hypothalamic inflammation via NF-κB associated inflammation activation in long-term PM2.5-exposed mice. Specifically, proopiomelanocortin-specific Rhbdf2 deficiency (Rhbdf2Pomc) and corresponding littermates control mice were used for the current study. After 24 weeks of PM2.5 inhalation, systemic-metabolism disorder was confirmed in WT mice in terms of impaired glucose tolerance, increased insulin resistance, and high blood pressure. Markedly, PM2.5-treated Rhbdf2Pomc mice displayed a significantly opposite trend in these parameters compared with those of the controls group. We next confirmed hypothalamic injury accompanied by abnormal POMC neurons loss, as indicated by increased inflammatory cytokines, chemokines, and oxidative-stress levels and decreased antioxidant activity. These results were further supported by blood routine examination. In summary, our findings suggest that Rhbdf2 plays an important role in exacerbating PM2.5-stimulated POMC neurons loss associated hypothalamic injury, thus providing a possible target for blocking pathological development of air pollution-associated diseases.Mercury (Hg) and its compounds are one of the most dangerous environmental pollutants and Hg pollution exists in soils in different degrees over the world. Phytoremediation of Hg-contaminated soils has attracted increasing attention for the advantages of low investment, in-situ remediation, potential economic benefits and so on. Searching for the hyperaccumulator of Hg and its application in practice become a research hotspot. In this context, we review the current literatures that introduce various experimental plant species for accumulating Hg and aided techniques improving the phytoremediation of Hg-contaminated soils. Experimental plant species for accumulating Hg and accumulation or translocation factor of Hg are listed in detail. The translocation factor (TF) is greater than 1.0 for some plant species, however, the bioaccumulation factor (BAF) is greater than 1.0 for Axonopus compressus only. Plant species, soil properties, weather condition, and the bioavailability and heterogeneity of Hg in soils are the main factors affecting the phytoremediation of Hg-contaminated soils. Chemical accelerator kinds and promoting effect of chemical accelerators for accumulating and transferring Hg by various plant species are also discussed. Potassium iodide, compost, ammonium sulphate, ammonium thiosulfate, sodium sulfite, sodium thiosulfate, hydrochloric acid and sulfur fertilizer may be selected to promote the absorption of Hg by plants. The review introduces transgenic gene kinds and promoting effect of transgenic plants for accumulating and transferring Hg in detail. Some transgenic plants can accumulate more Hg than non-transgenic plants. The composition of rhizosphere microorganisms of remediation plants and the effect of rhizosphere microorganisms on the phytoremediation of Hg-contaminated soils are also introduced. Some rhizosphere microorganisms can increase the mobility of Hg in soils and are beneficial for the phytoremediation.Peroxide/Zero-valent iron (Fe0) was reported to promote dewaterability of anaerobically digested sludge (ADS), but the mechanism of how Peroxide/Fe0 facilitates ADS dewatering is unknown. This study therefore aims to uncover the details of how Peroxide/Fe° elevates ADS dewaterability. Experimental results showed that with 0.6 g Fe0/g TSS and 0.08 g peroxide/g TSS, capillary suction time, specific resistance to filtration, and time to filtration of ADS was 50.7 %, 41.4 %, and 54.4 % of that in the control, respectively. In this condition, water content of sludge cake decreased from 91.2 % ± 0.5 % (the control) to 68.6 % ± 1.3 %. The mechanism explorations revealed that the elevated dewaterability was mainly caused by role of OH and Fe(II)/Fe(III) species during Peroxide/Fe° pretreatment. OH decreased the polysaccharides and proteins in extracellular polymeric substance (EPS), then injured the cytoderm &amp; cytomembrane through the releases of lactate dehydrogenase and N-acetylglucosamine, and further facilitated the decrease of intracellular substances, which disengaged the water trapped in ADS. In addition, the cell lysis caused by OH facilitated forming macro-pores. Moreover, OH converted the conformational structure of extracellular proteins, which may strengthen the ADS hydrophobicity, promoting the discharge of unbound water and ADS flocculation. Meanwhile, Fe(II)/Fe(III) benefited aggregating the denatured ADS particulates.A promising technology was proposed for the remediation of Cu and phenanthrene (PHE) co-contaminated soil. Firstly, Cu and PHE were simultaneously removed from soil using an extraction agent containing ethylenediaminetetraacetic acid (EDTA) and Tween 80 (TW80). Specifically, Cu was mobilized by the chelation of EDTA while PHE was desorpted from soil by TW80 micelles. https://www.selleckchem.com/products/bay-2402234.html At 20 mL g-1 of liquid to soil ratio, 10 g L-1 TW80 and 1 mM EDTA, 73.5% Cu and 68.1% PHE were removed by soil washing. The extraction agent was then recovered from effluent by photoelectro-persulfate (PE/PS) process after soil washing. Under the conditions of 10 mM PS, 4 mA cm-2 current density, natural pH of 3.5 and 150 min treatment, 83.6% Cu was reduced to elemental copper but only 36.8% EDTA was recovered, while 99.6% PHE was eliminated and 94.0% TW80 was recovered. The result of quenching experiments indicated PHE was predominantly oxidized by sulfate radical, though hydroxyl radical and singlet oxygen were also identified by electron paramagnetic resonance technique.